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Salvatore Rizza Selected Research

Neoplasms (Cancer)

1/2023GSNOR deficiency promotes tumor growth via FAK1 S-nitrosylation.
1/2022Lamin A/C impairments cause mitochondrial dysfunction by attenuating PGC1α and the NAMPT-NAD+ pathway.
1/2022Redox proteome analysis of auranofin exposed ovarian cancer cells (A2780).
1/2021AMBRA1 regulates cyclin D to guard S-phase entry and genomic integrity.
1/2021Screening of metabolic modulators identifies new strategies to target metabolic reprogramming in melanoma.
10/2020Exploiting S-nitrosylation for cancer therapy: facts and perspectives.
1/2020Mitophagy contributes to alpha-tocopheryl succinate toxicity in GSNOR-deficient hepatocellular carcinoma.
1/2020When S-Nitrosylation Gets to Mitochondria: From Signaling to Age-Related Diseases.
1/2016Tumor Suppressor Roles of the Denitrosylase GSNOR.
1/2016S-nitrosylation of the Mitochondrial Chaperone TRAP1 Sensitizes Hepatocellular Carcinoma Cells to Inhibitors of Succinate Dehydrogenase.
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Salvatore Rizza Research Topics

Disease

12Neoplasms (Cancer)
01/2023 - 01/2012
2Melanoma (Melanoma, Malignant)
01/2021 - 01/2021
2Hepatocellular Carcinoma (Hepatoma)
01/2020 - 01/2016
2Carcinogenesis
01/2016 - 01/2012
1Ovarian Neoplasms (Ovarian Cancer)
01/2022
1Progeria (Hutchinson Gilford Syndrome)
01/2022
1Mitochondrial Diseases (Mitochondrial Disease)
01/2022
1Premature Aging
01/2022
1Laminopathies
01/2022
1Genomic Instability
01/2021
1Ischemia
01/2020
1Parkinson Disease (Parkinson's Disease)
01/2015
1Hypoxia (Hypoxemia)
01/2015
1Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
01/2015
1Atrophy
08/2014

Drug/Important Bio-Agent (IBA)

4EnzymesIBA
01/2023 - 01/2015
4glutathione-independent formaldehyde dehydrogenase (formaldehyde dehydrogenase)IBA
01/2023 - 01/2015
4Proteins (Proteins, Gene)FDA Link
01/2022 - 01/2012
2Nitric Oxide (Nitrogen Monoxide)FDA Link
01/2023 - 08/2014
2Focal Adhesion Kinase 1IBA
01/2023 - 01/2021
2Succinic Acid (Succinate)IBA
01/2020 - 01/2016
2S-NitrosothiolsIBA
08/2014 - 01/2012
1ElementsIBA
01/2023
1SuspensionsIBA
01/2023
1Transcription Factors (Transcription Factor)IBA
01/2022
1Auranofin (Ridaura)FDA Link
01/2022
1ChromatinIBA
01/2022
1ProteomeIBA
01/2022
1Lamin Type A (Lamin A)IBA
01/2022
1PhytochemicalsIBA
01/2021
1VemurafenibIBA
01/2021
1Retinoblastoma ProteinIBA
01/2021
1Cyclin-Dependent Kinases (cdk Proteins)IBA
01/2021
1Cyclin DIBA
01/2021
1Oncogene Proteins (Oncogene Protein)IBA
10/2020
1Cysteine (L-Cysteine)FDA Link
01/2020
1Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA
01/2016
1Protein SIBA
01/2016
1Succinate Dehydrogenase (Fumarate Reductase)IBA
01/2016
1cobaltous chloride (cobalt(II)chloride)IBA
01/2015
1Tyrosine (L-Tyrosine)FDA Link
08/2014
1Glutamine (L-Glutamine)FDA Link
09/2012
1Pyruvic Acid (Pyruvate)IBA
09/2012
1bromopyruvateIBA
09/2012

Therapy/Procedure

2Therapeutics
01/2021 - 10/2020
1Drug Therapy (Chemotherapy)
09/2012